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Correlation of ezrin expression pattern and clinical outcomes in ewing sarcoma. Sarcoma Celik, H. Ezrin Inhibition up-regulates stress response gene expression. Identification of novel ezrin inhibitors targeting metastatic osteosarcoma by screening open access malaria box. Cancer Ther. Chang, Y. Pancreatic cancer-derived small extracellular vesical Ezrin regulates macrophage polarization and promotes metastasis. Cancer Res. Chen, Q. Silence of ezrin modifies migration and actin cytoskeleton rearrangements and enhances chemosensitivity of lung cancer cells in vitro.

Zhonghua Zhong Liu Za Zhi 34, — Chen, Y. Rho kinase phosphorylation promotes ezrin-mediated metastasis in hepatocellular carcinoma. Chetry, M. Cancer 11, — Cihan, Y.

Clucas, J. ERM proteins in cancer progression. Crepaldi, T. Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells. Cui, Y. Expression of ezrin and phosphorylated Ezrin pEzrin in pancreatic ductal adenocarcinoma. Cancer Invest 28, — Denker, S. Di Cristofano, C. Phosphorylated ezrin is located in the nucleus of the osteosarcoma cell.

Elliott, B. The membrane cytoskeletal crosslinker ezrin is required for metastasis of breast carcinoma cells. Breast Cancer Res. Fadiel, A. Expression of ezrin and estrogen receptors during cervical carcinogenesis. Fathi, A. Prognostic significance of CD and ezrin expression in colorectal carcinoma. Federici, C. Pleiotropic function of ezrin in human metastatic melanomas.

Cancer , — Fehon, R. Organizing the cell cortex: the role of ERM proteins. Fievet, B. Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin. Fouassier, L. Gary, R. Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site.

Cell 6, — Gautreau, A. Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane. Gavert, N. Nuclear factor-kappaB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells.

Ghaffari, A. Intravital imaging reveals systemic ezrin inhibition impedes cancer cell migration and lymph node metastasis in breast cancer. Gloerich, M. Rap2A links intestinal cell polarity to brush border formation. Haga, R. Rho GTPases: regulation and roles in cancer cell biology. Small GTPases 7, — Hao, J. Hashimoto, K. Concomitant expression of ezrin and HER2 predicts distant metastasis and poor prognosis of patients with salivary gland carcinomas.

Hata, K. The difference in Ezrin-pAkt signaling axis between lepidic and papillary predominant invasive adenocarcinomas of the lung. Heiska, L. Src phosphorylates ezrin at tyrosine and induces a phosphospecific association between ezrin and a kelch-repeat protein family member. Hiscox, S. Horwitz, V. Ezrin is associated with disease progression in ovarian carcinoma. PLoS One e Hoskin, V.

Ezrin, more than a metastatic detERMinant? Oncotarget 10, — Hu, K. Ilmonen, S. Ezrin in primary cutaneous melanoma. Ivetic, A. Immunology , — Janiszewska, M. Cell adhesion in cancer: beyond the migration of single cells. Jia, M. Ezrin, a membrane cytoskeleton cross-linker protein, as a marker of epithelial damage in asthma.

Care Med. Jin, J. Ezrin overexpression predicts the poor prognosis of gastric adenocarcinoma. Jin, T. Prognostic implications of ezrin and phosphorylated ezrin expression in non-small cell lung cancer. BMC Cancer Karmakar, S. Kawaguchi, K. Khanna, C. The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis.

Kobel, M. Kocher, H. Ezrin interacts with cortactin to form podosomal rosettes in pancreatic cancer cells. Gut 58, — Kolegova, E. Kong, J. Ezrin contributes to cervical cancer progression through induction of epithelial-mesenchymal transition. Oncotarget 7, — High expression of ezrin predicts poor prognosis in uterine cervical cancer. Krishnan, K. Metastasis 23, — Lee, H. Clinicopathologic implication of ezrin expression in non-small cell lung cancer. Korean J. Leiphrakpam, P. Ezrin expression and cell survival regulation in colorectal cancer.

Li, J. Prognostic value of ezrin in various cancers: a systematic review and updated meta-analysis. Li, L. Ezrin is associated with gastric cancer progression and prognosis. Li, M. Overexpression of ezrin and galectin-3 as predictors of poor prognosis of cervical cancer.

Li, N. Ezrin promotes breast cancer progression by modulating AKT signals. Li, Q. Expression of ezrin correlates with malignant phenotype of lung cancer, and in vitro knockdown of ezrin reverses the aggressive biological behavior of lung cancer cells. Liang, F.

Association of ezrin expression with the progression and prognosis of gastrointestinal cancer: a meta-analysis. Oncotarget 8, — Lin, L. Association between ezrin protein expression and the prognosis of colorectal adenocarcinoma. Liu, Y. Ezrin is essential for the entry of Japanese encephalitis virus into the human brain microvascular endothelial cells. Emerg Microbes Infect 9, — Lowery, A. Dysregulated miR inhibits migration in breast cancer cells.

Mak, H. Ezrin phosphorylation on tyrosine regulates invasion and metastasis of breast cancer cells. Malmstrom, P. Validation of the ezrin, CK20, and Ki as potential predictive markers for BCG instillation therapy of non-muscle-invasive bladder cancer. Matsui, T. McClatchey, A. Merlin and ERM proteins: unappreciated roles in cancer development?

Cancer 3, — Meng, Y. Ezrin promotes invasion and metastasis of pancreatic cancer cells. Michie, K. Moodley, S. RET isoform-specific interaction with scaffold protein Ezrin promotes cell migration and chemotaxis in lung adenocarcinoma. Lung Cancer , — Morales, F.

Overexpression of ezrin inactivates NF2 tumor suppressor in glioblastoma. Nakamura, N. Phosphorylation of ERM proteins at filopodia induced by Cdc Genes Cells 5, — Okamura, D.

Ezrin expression is associated with hepatocellular carcinoma possibly derived from progenitor cells and early recurrence after surgical resection. Osawa, H. The role of the membrane cytoskeleton cross-linker ezrin in medulloblastoma cells. Oncol 11, — Paige, M. Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma. Palou, J. Protein expression patterns of ezrin are predictors of progression in T1G3 bladder tumours treated with nonmaintenance bacillus calmette-guerin.

Patara, M. Ezrin expression as a prognostic marker in colorectal adenocarcinoma. Pore, D. Identification of Ezrin-Radixin-Moesin proteins as novel regulators of pathogenic B-cell receptor signaling and tumor growth in diffuse large B-cell lymphoma. Leukemia 29, — Poullet, P. Ezrin interacts with focal adhesion kinase and induces its activation independently of cell-matrix adhesion. Prag, S. Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc Cell 18, — Quan, C.

Cancer Manag. Ren, L. Role of ezrin in osteosarcoma metastasis. Riecken, L. Roy, C. A dual involvement of the amino-terminal domain of ezrin in F- and G-actin binding. Saavedra, K. Epigenetic alterations in preneoplastic and neoplastic lesions of the cervix.

Epigenetics Saito, S. Mechanisms underlying cancer progression caused by ezrin overexpression in tongue squamous cell carcinoma. Saygideger-Kont, Y. Ezrin enhances EGFR signaling and modulates erlotinib sensitivity in non-small cell lung cancer cells. Neoplasia 18, — Shiue, H. Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation. Slik, K. Srivastava, J. Src-dependent ezrin phosphorylation in adhesion-mediated signaling. Cell 16, — Sun, N. Tang, F. Tuna, B.

Ezrin immunoreactivity in renal cell carcinomas. Viswanatha, R. Wald, F. Atypical protein kinase C iota activates ezrin in the apical domain of intestinal epithelial cells. Wang, G. MicroRNA regulates Ezrin expression in lung cancer cells. Wu, B. Baicalein mediates inhibition of migration and invasiveness of skin carcinoma through Ezrin in A cells.

Yang, H. Increased ezrin expression and activation by CDK5 coincident with acquisition of the senescent phenotype. Phosphorylation of ezrin by cyclin-dependent kinase 5 induces the release of Rho GDP dissociation inhibitor to inhibit Rac1 activity in senescent cells.

Yeh, C. Expression of ezrin is associated with invasion and dedifferentiation of hepatitis B related hepatocellular carcinoma.

Yin, L. Ezrin orchestrates signal transduction in airway cells. Yu, N. Zacapala-Gomez, A. Ezrin and E-cadherin expression profile in cervical cytology: a prognostic marker for tumor progression in cervical cancer. Zhang, X. Regulation of ezrin tension by S-nitrosylation mediates non-small cell lung cancer invasion and metastasis. Theranostics 9, — Expression and clinical significance of ezrin in non—small-cell lung cancer.

Lung Cancer 13, — Zhang, Y. Osteosarcoma metastasis: prospective role of ezrin. Cell Dev. This is your profile URL. Pick one that's 25 characters or less and includes a letter. You can throw in numbers, dots and dashes, too. Pick one that's hard-to-crack, only known by you, and at least 6 characters long.

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